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Fb2 DNA Replication and Human Disease (COLD SPRING HARBOR MONOGRAPH SERIES) ePub

by Melvin L. DePamphilis

Category: Medicine
Subcategory: Medical Books
Author: Melvin L. DePamphilis
ISBN: 0879697660
ISBN13: 978-0879697662
Language: English
Publisher: Cold Spring Harbor Laboratory Press; 1st edition (July 25, 2006)
Pages: 814
Fb2 eBook: 1946 kb
ePub eBook: 1123 kb
Digital formats: lrf doc rtf txt

Series: COLD SPRING HARBOR MONOGRAPH SERIES (Book 46).

ISBN-13: 978-0879697662. this book provides a broad and current synthesis of our understanding of genome duplication and it should be on the bookshelves of all students of DNA replication. -Carol S. Newlon, Nature Cell Biology. Series: COLD SPRING HARBOR MONOGRAPH SERIES (Book 46). Hardcover: 814 pages.

Start by marking DNA Replication and Human Disease as Want to Read .

Start by marking DNA Replication and Human Disease as Want to Read: Want to Read savin. ant to Read. This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of targeted therapeutics is also addressed.

DNA Damage and Human Disease, 377 Errol C. Friedberg. DNA Polymerases and the Fidelity of DNA Replication, 391 Polina V. Scherbakova and Thomas A. Kunkel. The Role of RF-C and PCNA Proteins in Maintaining Genomic Stability, 411 Toshiki Tsurimoto

DNA Damage and Human Disease, 377 Errol C. The Role of RF-C and PCNA Proteins in Maintaining Genomic Stability, 411 Toshiki Tsurimoto. DNA Helicases and Human Disease, 435 Ashwini S. Kamath-Loeb, Michael Fry, and Lawrence A. Loeb. DNA Replication, Repeat Instability, and Human Disease, 461 John D. Cleary, Albert R. La Spada, and Christopher E. Pearson. DNA Replication and Cancer, 481 William C. Burhans, Antony M. Carr, and Geoffrey M. Wahl.

In: DePamphilis ML (ed) DNA replication and human disease, Cold spring harbor monograph series. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp 89–104Google Scholar

In: DePamphilis ML (ed) DNA replication and human disease, Cold spring harbor monograph series. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp 89–104Google Scholar. Wilmes GM, Archambault V, Austin RJ, Jacobson MD, Bell SP, Cross FR (2004) Interaction of the S-phase cyclin clb5 with an Rxl docking sequence in the initiator protein orc6 provides an origin-localized replication control switch.

Melvin L. DePamphilis, National Institutes of Health, Maryland More. About Cold Spring Harbor Laboratory Press

Melvin L. About Cold Spring Harbor Laboratory Press. Since 1933, the publication of books and other media by Cold Spring Harbor Laboratory Press has assisted the Laboratory's purpose of furthering the advance and spread of scientific knowledge. The reproduction, modification, storage in a retrieval system, or retransmission, in any form or by any means, electronic, mechanical, or otherwise, for reasons other than personal, noncommercial use is strictly prohibited without prior written permission.

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It is one of 68 institutions supported by the Cancer Centers Program of the . National Cancer Institute (NCI) and has been an NCI-designated Cancer Center since 1987. The Laboratory is one of a handful of institutions that played a central role in the development of molecular genetics and molecular biology.

When DNA replication is inhibited by aphidicolin or l-mimosine this genome-wide demethylation is still observed. Transfection of cells with an antisense morpholino oligonucleotide to 5-methylcytosine DNA glycosylase (G/T mismatch DNA glycosylase) decreases both the activity of the enzyme and genome-wide demethylation

Publisher:Cold Spring Harbor Laboratory Press.

At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. Publisher:Cold Spring Harbor Laboratory Press.

Methods and Resources Packages Book any 6 banner ad at regular price in Cold Spring Harbor Protocols and receive a FREE enhanced listing on BioSupplyNet.

At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA! And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. How is this feat accomplished? What happens when errors occur? This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of targeted therapeutics is also addressed. At least 160 proteins are involved in replicating the human genome, and at least 40 diseases are caused by aberrant DNA replication, 35 by mutations in genes required for DNA replication or repair, 7 by mutations generated during mitochondrial DNA replication, and more than 40 by DNA viruses. Consequently, a growing number of therapeutic drugs are targeted to DNA replication proteins. This authoritative volume provides a rich source of information for researchers, physicians, and teachers, and will stimulate thinking about the relevance of DNA replication to human disease.
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